Endocrine Abstracts

It has been shown that adiponectin (AN) has antidiabetic, antiatherosclerotic and antiinflammatory activities. We analyzed serum AN levels in children with nonspecific infections. Forty-two prepubertal children (18 boys, 24 girls, age range: 14–163 months) admitted with fever ≥38 °C and nonspecific infection (upper respiratory tract infection, otitis, urine tract infections) symptoms were included. Their ideal body weights (IBW) for height were within 10...

Introduction: Gestational diabetes (GDM) has an important short and long-term health consequences for both the mother and her offspring. The aim of this study was to evaluate current metabolic status of women with GDM history and their offspring approximately at 10th year after delivery.Methods: 24 mothers who had GDM 10 years before (mean age 41.08±4.13 years and BMI 30.3±5.9) and their children (11 females, 13 males; mean age of 11.0±1.9...

Objective: Neonatal diabetes is caused by single gene mutations reducing pancreatic β-cell number or impairing β-cell function. Understanding the genetic underpinnings of rare diabetes subtypes highlights fundamental biological processes in β-cells. Our aim was to explore the genetic basis of a syndrome characterized by neonatal diabetes, microcephaly and epilepsy.Methods: We performed whole genome sequencing for 2 unrelated patients with ...